Moderna CEO: Could take weeks for more clarity on omicron Covid variant

Moderna CEO Stephane Bancel sits down with CNBC's Meg Tirrell and the 'Squawk Box' team to discuss how the company is responding to the omicron coronavirus variant. For access to live and exclusive video from CNBC subscribe to CNBC PRO: https://cnb.cx/2NGeIvi

Moderna CEO Stephane Bancel on Monday said it will take months to develop and ship a vaccine that specifically targets the omicron variant of the virus that causes Covid-19.

However, a higher 100-microgram dose of the company’s booster shot could be ready much sooner.

“The higher dose could be done right away but it will be months before the omicron specific variant is ready to ship in massive quantities,” Bancel told CNBC’s “Squawk Box.”

Bancel said Moderna believes the omicron variant is highly infectious, but it will take at least two weeks to determine how much the mutations have impacted the efficacy of the vaccines currently on the market.

“Depending on how much it dropped, we might decide on the one hand to give a higher dose of the current vaccine around the world to protect people, maybe people at very high risk, the immunocompromised, and the elderly should need a fourth dose” he said.

Dr. Scott Gottlieb, a former commissioner of the Food and Drug Administration, told CNBC that the FDA can move fast to approve a new vaccine to target omicron.

“I think the FDA is in a position to move very quickly at this point because they understand the basic platform, the manufacturing has been inspected, they understand the risk-benefit of the mRNA platforms generally,” said Gottlieb, who is a Pfizer board member.

Pfizer CEO Albert Bourla said the impact of omicron on the company’s two-dose vaccine remains to be seen.

“I don’t think that the result will be the vaccines don’t protect,” Bourla told CNBC. “I think the result could be, which we don’t know yet, the vaccines protect less.”

Bourla said Pfizer has already begun work on manufacturing a new vaccine if necessary. The company made its first DNA template Friday, he said, the initial step in the development process.

“We have made multiple times clear that we would be able to have the vaccine in less than 100 days,” Bourla said. He noted the company was able to create vaccines for the beta and delta variants quickly, though they ultimately weren’t used because the original shots remained effective.

The World Health Organization, in a technical paper published Sunday, said omicron has more than 30 mutations on the spike protein that binds to human cells. These mutations are associated with higher transmission and potentially reduced antibody protection, according to the paper.

Omicron was first identified in South Africa’s Gauteng province where Johannesburg is located. Moderna’s Bancel warned the variant is spreading globally already. He pointed to flights that arrived in Amsterdam from South Africa on Friday in which 61 of 624 passengers tested positive for Covid. At least 13 of them are infected with the omicron strain as health authorities continue to sequence the samples, according to the Dutch National Institute for Public Health and the Environment.

“We also believe it is already present in most countries,” Bancel said. “I believe most countries that have direct flights from South Africa in the last seven to 10 days already have cases in their country that they may not be aware of.”

The U.S. has banned entry for noncitizens who have traveled in South Africa and seven other nations in the region in the past 14 days. The United Kingdom and the European Union have implemented similar travel restrictions.

The U.S. Centers for Disease Control and Prevention said Friday that a case has not yet been identified in the country. However, White House chief medical advisor Dr. Anthony Fauci said on Sunday that the variant will inevitably arrive in the U.S. Two cases of omicron have been identified in Ontario, Canada, according to the country’s public health agency.

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